Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 15/20 | 0.62 |
| ▸ | CA2 | P00918 | 15/20 | 0.62 |
| ▸ | CA4 | P22748 | 6/20 | 0.62 |
| ▸ | CA12 | O43570 | 4/20 | 0.62 |
| ▸ | CA9 | Q16790 | 4/20 | 0.62 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | PPID | Q08752 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7512416 | 0.94 | CA1 (0.71) | CA1CA2CA4CA12CA9 | |
| SCHEMBL7504982 | 0.85 | CA2 (0.49) | CA1CA2CA4CA12CA9 | |
| SCHEMBL14100114 | 0.81 | TPSAB1 (0.50) | CA1CA2CA12CA9TPSAB1 | |
| SCHEMBL9856623 | 0.79 | CA1 (0.68) | CA1CA2CA4CA12CA9 | |
| SCHEMBL21781874 | 0.77 | CA1 (0.64) | CA1CA2TPSAB1EPHX2PPID | |
| SCHEMBL18868428 | 0.77 | ALDH1A1 (0.61) | CA1CA2CA12CA9TPSAB1 | |
| SCHEMBL9705794 | 0.77 | CA1 (0.68) | CA1CA2CA4CA12CA9 | |
| SCHEMBL25296370 | 0.76 | CA1 (0.64) | CA1CA2CA4CA12CA9 | |
| SCHEMBL15651444 | 0.75 | PPID (0.54) | TPSAB1EPHX2PPID | |
| SCHEMBL3517253 | 0.75 | TPSAB1 (0.53) | CA1CA2TPSAB1EPHX2PPID |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0353295-B1 | NOVEL AND IMPROVED ANTIBODIES FOR SITE SPECIFIC ATTACHMENT OF COMPOUNDS | CYTOGEN CORP (US) | 1994-04-06 | — | — | EP | claimed |
| EP-0382796-A4 | METHOD FOR THE PREPARATION OF ANTIBODY-FRAGMENT CONJUGATES | — | 1991-08-28 | — | — | EP | claimed |
| EP-0382796-A1 | METHOD FOR THE PREPARATION OF ANTIBODY-FRAGMENT CONJUGATES | CYTOGEN CORPORATION (US) | 1990-08-22 | — | — | EP | claimed |
| US-4937183-A | Therapy, diagnostis immunology | CYTOGEN CORPORATION (US) | 1990-06-26 | — | — | US | claimed |
| WO-1989007269-A1 | METHOD FOR THE PREPARATION OF ANTIBODY-FRAGMENT CONJUGATES | CYTOGEN CORPORATION (US) | 1989-08-10 | — | — | WO | claimed |
| US-4741900-A | Antibody-metal ion complexes | CYTOGEN CORPORATION (US) | 1988-05-03 | — | — | US | claimed |