SCHEMBL944165

SCHEMBL944165

CCc1cc(Cl)cc(Br)c1CC(Cl)(Cl)Br

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SIRT2 Q8IXJ6 2/20 0.30
ERN1 O75460 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL943717 0.89 SIRT2 (0.30) SIRT2ERN1
SCHEMBL944265 0.83
SCHEMBL14490581 0.71 ALDH1A1 (0.34)
SCHEMBL23862482 0.71 TSHR (0.37)
SCHEMBL944494 0.70 GAA (0.44) SIRT2ERN1
SCHEMBL946031 0.69 HTT (0.38) SIRT2ERN1
SCHEMBL13888155 0.69 ERN1 (0.50) ERN1
SCHEMBL944650 0.69 SCN4A (0.32)
SCHEMBL320946 0.69 ALDH1A1 (0.36) SIRT2ERN1
SCHEMBL19126569 0.67 CYP1A2 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7875753-B2 formed by reacting aryldiazonium bromide with vinylidene chloride in presence of copper salt and bromide source BAYER CROPSCIENCE AG (DE) 2011-01-25 US disclosed
US-7875753-B2 formed by reacting aryldiazonium bromide with vinylidene chloride in presence of copper salt and bromide source BAYER CROPSCIENCE AG (DE) 2011-01-25 US disclosed
US-7875753-B2 formed by reacting aryldiazonium bromide with vinylidene chloride in presence of copper salt and bromide source BAYER CROPSCIENCE AG (DE) 2011-01-25 US disclosed
WO-2010105739-A1 AROMATIC 2-BROMO-2,2-DICHLOROETHYL COMPOUNDS AND METHODS FOR THE PRODUCTION THEREOF BAYER CROPSCIENCE AG (DE) 2010-09-23 WO disclosed
US-20100234651-A1 2-Bromo-2,2-Dichloroethyl Aromatics and Process for Preparation Thereof BAYER CROPSCIENCE AG (DE) 2010-09-16 US disclosed
US-20100234651-A1 2-Bromo-2,2-Dichloroethyl Aromatics and Process for Preparation Thereof BAYER CROPSCIENCE AG (DE) 2010-09-16 US disclosed
US-20100234651-A1 2-Bromo-2,2-Dichloroethyl Aromatics and Process for Preparation Thereof BAYER CROPSCIENCE AG (DE) 2010-09-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100234651-A1 2-Bromo-2,2-Dichloroethyl Aromatics and Process for Preparation Thereof AR, AHR, ADRA2C SIRT2 1497/4885ERN1 4096/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.