Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14661247 | 0.84 | MAPT (0.46) | GAAKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL13527342 | 0.83 | ALDH1A1 (0.48) | GAAKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL3001748 | 0.83 | KDM4E (0.41) | GAAKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL12658255 | 0.81 | ALDH1A1 (0.44) | GAAKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL1475954 | 0.78 | HSP90AB1 (0.43) | GAAKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL20563105 | 0.78 | ALDH1A1 (0.38) | GAAKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL1782875 | 0.76 | ABCB1 (0.31) | — | |
| SCHEMBL1782878 | 0.76 | LMNA (0.32) | GAALMNAMAOB | |
| SCHEMBL1782880 | 0.76 | ABCB1 (0.31) | — | |
| SCHEMBL23243620 | 0.74 | MAPT (0.43) | GAAKMT2AMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101195599-B | 2,4, 6-phenyl-substituted cyclic keto-enols | BAYER CROPSCIENCE AG | 2013-04-10 | — | — | CN | disclosed |
| CN-102516155-A | 2,4, 6-phenyl-substituted cyclic keto-enols | BAYER CROPSCIENCE AG | 2012-06-27 | — | — | CN | disclosed |
| US-20110092368-A1 | 2,4,6-Phenyl-substituted cyclic ketoenols | FISCHER REINER | 2011-04-21 | — | — | US | disclosed |
| US-7888285-B2 | 2,4,6-phenyl substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2011-02-15 | — | — | US | disclosed |
| US-7875753-B2 | formed by reacting aryldiazonium bromide with vinylidene chloride in presence of copper salt and bromide source | BAYER CROPSCIENCE AG (DE) | 2011-01-25 | — | — | US | disclosed |
| US-20100234651-A1 | 2-Bromo-2,2-Dichloroethyl Aromatics and Process for Preparation Thereof | BAYER CROPSCIENCE AG (DE) | 2010-09-16 | — | — | US | disclosed |
| CN-101195599-A | 2,4, 6-phenyl-substituted cyclic keto-enols | BAYER CROPSCIENCE AG (DE) | 2008-06-11 | — | — | CN | disclosed |
| US-20070015664-A1 | 2,4,6-Phenyl substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2007-01-18 | — | — | US | disclosed |
| CN-1787994-A | 2,4, 6-phenyl-substituted cyclic keto-enols | BAYER CROPSCIENCE AG (DE) | 2006-06-14 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070015664-A1 | 2,4,6-Phenyl substituted cyclic ketoenols | CYP4X1, KDM4E, KCNE1 | GAA 1055/4885KMT2A 321/4885MEN1 4847/4885 |
| US-20110092368-A1 | 2,4,6-Phenyl-substituted cyclic ketoenols | CYP4X1, KDM4E, PDHX | GAA 1079/4885KMT2A 276/4885MEN1 4855/4885 |
| US-20100234651-A1 | 2-Bromo-2,2-Dichloroethyl Aromatics and Process for Preparation Thereof | AR, AHR, ADRA2C | GAA 2050/4885KMT2A 383/4885MEN1 1297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.