Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 4/20 | 0.43 |
| ▸ | FABP4 | P15090 | 4/20 | 0.43 |
| ▸ | FABP3 | P05413 | 3/20 | 0.43 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8337206 | 0.89 | DHODH (0.43) | ALDH1A1CYP2C9PTGESALOX5HPGD | |
| Hydrochloric Acid SCHEMBL5410407 | 0.87 | DHODH (0.42) | ALDH1A1CYP2C9PTGESALOX5HPGD | |
| SCHEMBL11668861 | 0.81 | ALDH1A1 (0.65) | ALDH1A1CYP2C9PTGESALOX5HPGD | |
| SCHEMBL1305232 | 0.81 | ALDH1A1 (0.49) | ALDH1A1CYP2C9PTGESALOX5HPGD | |
| SCHEMBL30120641 | 0.81 | ALDH1A1 (0.65) | ALDH1A1CYP2C9PTGESALOX5HPGD | |
| SCHEMBL9441952 | 0.80 | DHODH (0.44) | ALDH1A1DHODHGAAALOX15 | |
| SCHEMBL9441954 | 0.80 | ALDH1A1 (0.47) | ALDH1A1HPGDHSD17B10L3MBTL1POLB | |
| SCHEMBL28071570 | 0.78 | ALDH1A1 (0.52) | ALDH1A1CYP2C9PTGESALOX5HPGD | |
| SCHEMBL14578175 | 0.77 | ALOX15 (0.58) | ALDH1A1HPGDHSD17B10POLBTDP1 | |
| SCHEMBL7650669 | 0.74 | MAPK1 (0.62) | ALDH1A1CYP2C9PTGESALOX5HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250541-A | Neurological disorders | FIDIA S.P.A. (IT) | 1993-10-05 | — | — | US | disclosed |
| WO-1991001973-A1 | KYNURENIC ACID DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FIDIA S.P.A. (IT) | 1991-02-21 | — | — | WO | disclosed |