Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4589105 | 0.84 | LMNA (0.49) | LMNA | |
| SCHEMBL10587075 | 0.82 | LMNA (0.61) | LMNA | |
| SCHEMBL1795967 | 0.80 | LMNA (0.43) | LMNA | |
| SCHEMBL1795969 | 0.80 | LMNA (0.43) | LMNA | |
| SCHEMBL11309797 | 0.78 | KDM4E (0.47) | — | |
| SCHEMBL11311855 | 0.78 | SLC6A1 (0.45) | LMNA | |
| SCHEMBL5069171 | 0.77 | LMNA (0.48) | LMNA | |
| SCHEMBL5069168 | 0.77 | LMNA (0.48) | LMNA | |
| SCHEMBL5067551 | 0.77 | LMNA (0.48) | LMNA | |
| SCHEMBL4622794 | 0.77 | LMNA (0.48) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0572449-A1 | (AMIDOMETHYL)NITROGEN HETEROCYCLIC ANALGESICS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-12-08 | — | — | EP | disclosed |
| US-5254569-A | Side effect reduction; diuretics; anticonvulsants | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-10-19 | — | — | US | disclosed |
| WO-1992012128-A1 | (AMIDOMETHYL)NITROGEN HETEROCYCLIC ANALGESICS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1992-07-23 | — | — | WO | disclosed |