Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | STAT3 | P40763 | 2/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9442737 | 0.87 | KDM4E (0.59) | HPGDKDM4EALDH1A1HSD17B10KMT2A | |
| SCHEMBL29895231 | 0.86 | STAT3 (0.61) | HPGDKDM4EALDH1A1HSD17B10KMT2A | |
| SCHEMBL6756451 | 0.86 | STAT3 (0.61) | HPGDKDM4EALDH1A1HSD17B10KMT2A | |
| SCHEMBL9442745 | 0.85 | HPGD (0.48) | HPGDKDM4EALDH1A1HSD17B10KMT2A | |
| SCHEMBL11229199 | 0.84 | KMT2A (0.56) | HPGDKDM4EALDH1A1HSD17B10KMT2A | |
| SCHEMBL10574238 | 0.84 | KDM4E (0.55) | HPGDKDM4EALDH1A1HSD17B10KMT2A | |
| SCHEMBL9442768 | 0.84 | KMT2A (0.48) | HPGDKDM4EALDH1A1HSD17B10KMT2A | |
| SCHEMBL9442764 | 0.83 | LMNA (0.58) | HPGDKDM4EALDH1A1HSD17B10KMT2A | |
| SCHEMBL10459763 | 0.82 | STAT3 (0.56) | HPGDKDM4EALDH1A1HSD17B10KMT2A | |
| SCHEMBL10623495 | 0.81 | KMT2A (0.55) | HPGDKDM4EALDH1A1HSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5233091-A | Cyclopropyl fluoroaniline as chemical intermediate for bactericides | PFIZER INC. (US) | 1993-08-03 | — | — | US | disclosed |
| US-5104868-A | Bactericides | PFIZER INC. (US) | 1992-04-14 | — | — | US | disclosed |
| US-5103040-A | Bactericides | PFIZER INC. (US) | 1992-04-07 | — | — | US | disclosed |
| US-5039682-A | Bactericides | PFIZER INC. (US) | 1991-08-13 | — | — | US | disclosed |
| EP-0348088-A1 | 6-Fluoro-1,4-dihydroquinol-4-one-3-carboxylic acid derivatives and intermediates therefor | PFIZER INC. (US) | 1989-12-27 | — | — | EP | disclosed |