Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | IAPP | P10997 | 2/20 | 0.49 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 3/20 | 0.33 |
| ▸ | MMP12 | P39900 | 3/20 | 0.33 |
| ▸ | MMP13 | P45452 | 3/20 | 0.33 |
| ▸ | MMP14 | P50281 | 3/20 | 0.33 |
| ▸ | MMP8 | P22894 | 2/20 | 0.33 |
| ▸ | MMP16 | P51512 | 2/20 | 0.33 |
| ▸ | MMP1 | P03956 | 2/20 | 0.33 |
| ▸ | MMP3 | P08254 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9120545 | 0.98 | ALDH1A1 (0.50) | ALDH1A1LMNAIAPPMYCTDP1 | |
| SCHEMBL10781544 | 0.83 | IAPP (0.53) | ALDH1A1LMNAIAPPTDP1 | |
| SCHEMBL9120050 | 0.83 | ALDH1A1 (0.49) | ALDH1A1LMNAIAPPTDP1SMN1; SMN2 | |
| SCHEMBL15303316 | 0.82 | KEAP1 (0.48) | ALDH1A1TDP1SMN1; SMN2MAPTMMP2 | |
| SCHEMBL9444064 | 0.81 | ALDH1A1 (0.47) | ALDH1A1LMNAIAPPTDP1SMN1; SMN2 | |
| SCHEMBL4202392 | 0.81 | MYC (0.47) | ALDH1A1LMNAMYCTDP1SMN1; SMN2 | |
| SCHEMBL30446463 | 0.81 | MYC (0.47) | ALDH1A1LMNAMYCTDP1SMN1; SMN2 | |
| SCHEMBL27680075 | 0.80 | MYC (0.44) | LMNAMYCSMN1; SMN2HPGDCTSB | |
| SCHEMBL16494379 | 0.80 | MMP2 (0.51) | ALDH1A1LMNAIAPPMMP2MMP12 | |
| SCHEMBL31319091 | 0.78 | MYC (0.46) | LMNAMYCSMN1; SMN2HPGDCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5220062-A | PROCESS FOR THE PREPARATION OF BENEZENESULFONAMIDES | CIBA-GEIGY CORPORATION (US) | 1993-06-15 | — | — | US | disclosed |