Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | MMP9 | P14780 | 3/20 | 0.34 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | MMP3 | P08254 | 2/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP7 | P09237 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9579929 | 0.79 | HTT (0.47) | HTTSMN1; SMN2LMNATDP1L3MBTL1 | |
| SCHEMBL5664519 | 0.79 | HTT (0.47) | HTTSMN1; SMN2LMNATDP1L3MBTL1 | |
| SCHEMBL9579965 | 0.79 | HTT (0.47) | HTTSMN1; SMN2LMNATDP1L3MBTL1 | |
| SCHEMBL21446843 | 0.70 | HTT (0.61) | HTTSMN1; SMN2LMNATDP1L3MBTL1 | |
| SCHEMBL3781114 | 0.69 | ALDH1A1 (0.42) | LMNAPKMALDH1A1POLBMAPT | |
| SCHEMBL10030394 | 0.67 | MAPT (0.47) | HTTSMN1; SMN2LMNATDP1L3MBTL1 | |
| SCHEMBL15070045 | 0.67 | ESR1 (0.53) | ESR1ESR2TDP1ALDH1A1POLB | |
| SCHEMBL3060894 | 0.67 | ESR1 (0.75) | ESR1ESR2ALDH1A1 | |
| SCHEMBL9579795 | 0.67 | HTT (0.41) | HTTSMN1; SMN2LMNATDP1L3MBTL1 | |
| SCHEMBL9937019 | 0.66 | ESR1 (0.52) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5244723-A | Filaments, tow, and webs formed by hydraulic spinning | KIMBERLY-CLARK CORPORATION (US) | 1993-09-14 | — | — | US | disclosed |