Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 7/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | PKM | P14618 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9579929 | 1.00 | HTT (0.47) | HTTSMN1; SMN2ALDH1A1PKML3MBTL1 | |
| SCHEMBL5664519 | 0.96 | HTT (0.47) | HTTSMN1; SMN2ALDH1A1PKML3MBTL1 | |
| SCHEMBL3781114 | 0.88 | ALDH1A1 (0.42) | ALDH1A1PKMLMNAMAPTTSHR | |
| SCHEMBL9579795 | 0.85 | HTT (0.41) | HTTSMN1; SMN2ALDH1A1PKML3MBTL1 | |
| SCHEMBL9579897 | 0.84 | HTT (0.54) | HTTSMN1; SMN2ALDH1A1PKML3MBTL1 | |
| SCHEMBL9444071 | 0.79 | HTT (0.38) | HTTSMN1; SMN2ALDH1A1PKML3MBTL1 | |
| SCHEMBL23360750 | 0.77 | PKM (0.76) | HTTALDH1A1PKMMAPTNPC1 | |
| SCHEMBL818508 | 0.77 | HTR6 (0.50) | ALDH1A1PKMLMNAMAPTTSHR | |
| SCHEMBL8632609 | 0.74 | ALDH1A1 (0.55) | ALDH1A1PKMLMNAMAPTTSHR | |
| SCHEMBL9153268 | 0.73 | SMN1; SMN2 (0.47) | HTTSMN1; SMN2ALDH1A1TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532893-A2 | Depolymerization of polymers and their use in thermoset compositions and composites | HERCULES INCORPORATED (US) | 1993-03-24 | — | — | EP | disclosed |