SCHEMBL3781114

SCHEMBL3781114

[O]c1ccc(S(=O)(=O)c2cc[c]cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.42
HTR6 P50406 4/20 0.42
CYP3A4 P08684 2/20 0.42
GAA P10253 2/20 0.42
MAPK1 P28482 1/20 0.42
LMNA P02545 1/20 0.42
MPO P05164 1/20 0.42
CYP2C9 P11712 1/20 0.42
TSHR P16473 1/20 0.42
PKM P14618 4/20 0.38
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
MAPT P10636 2/20 0.33
POLB P06746 1/20 0.33
KDM4E B2RXH2 1/20 0.32
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32
HSD17B10 Q99714 1/20 0.32
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9579965 0.88 HTT (0.47) ALDH1A1GAAMAPK1LMNATSHR
SCHEMBL9579929 0.88 HTT (0.47) ALDH1A1GAAMAPK1LMNATSHR
SCHEMBL818508 0.87 HTR6 (0.50) ALDH1A1HTR6CYP3A4GAAMAPK1
SCHEMBL8632609 0.84 ALDH1A1 (0.55) ALDH1A1HTR6CYP3A4GAAMAPK1
SCHEMBL5664519 0.84 HTT (0.47) ALDH1A1GAAMAPK1LMNATSHR
SCHEMBL3052955 0.79 GAA (0.53) ALDH1A1HTR6CYP3A4GAAMAPK1
SCHEMBL9243675 0.79 ALDH1A1 (0.73) ALDH1A1HTR6CYP3A4GAAMAPK1
SCHEMBL9580065 0.79 HTR6 (0.41) ALDH1A1HTR6CYP3A4GAAMAPK1
SCHEMBL28422858 0.79 HTR6 (0.73) ALDH1A1HTR6CYP3A4GAAMAPK1
SCHEMBL310696 0.79 GAA (0.73) ALDH1A1CYP3A4GAACYP2C9PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3645600-A1 CORE-TO-SURFACE POLYMERIZATION FOR THE SYNTHESIS OF STAR POLYMERS AND USES THEREOF Massachusetts Institute of Technology (US) 2020-05-06 EP claimed
WO-2019006422-A1 CORE-TO-SURFACE POLYMERIZATION FOR THE SYNTHESIS OF STAR POLYMERS AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2019-01-03 WO claimed
EP-3039076-A1 COMPOSITION AND ARTICLE COMPRISING THERMOPLASTIC POLYURETHANE AND PARTICULATE ENGINEERING POLYMER SABIC Global Technologies B.V. (NL) 2016-07-06 EP claimed
WO-2015031292-A1 COMPOSITION AND ARTICLE COMPRISING THERMOPLASTIC POLYURETHANE AND PARTICULATE ENGINEERING POLYMER SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2015-03-05 WO claimed
CN-117754942-A Surface material for composite structures 塞特工业公司 2024-03-26 CN disclosed
CN-117296173-A membrane for proton conduction 托马斯·翰翎 2023-12-26 CN disclosed
CN-113547814-B Surface material for composite structures 塞特工业公司 2023-11-17 CN disclosed
CN-116847893-A Devices and methods for implanting cells secreting therapeutic compounds 豪夫迈·罗氏有限公司 2023-10-03 CN disclosed
CN-108430874-B Multifunctional surface material with burn-through resistance 塞特工业公司 2022-02-18 CN disclosed
CN-113547814-A Surfacing material for composite structures 塞特工业公司 2021-10-26 CN disclosed
CN-113166638-A Photonic up-conversion nanocapsules for 3D printing and other applications 哈佛学院院长及董事 2021-07-23 CN disclosed
CN-112625535-A Ion complexing material having ability to inhibit attachment of biological substance and method for producing same 日产化学工业株式会社 2021-04-09 CN disclosed
EP-0801603-A4 COATED SHEET MATERIAL AND METHOD WARE TECHNOLOGIES L C A (US) 1998-09-16 EP disclosed
EP-0858070-A1 DISC MEDIUM SUBSTRATE AND DISC DEVICE SONY CORPORATION (JP) 1998-08-12 EP disclosed
EP-0801603-A1 COATED SHEET MATERIAL AND METHOD A*Ware Technologies, L.C. (US) 1997-10-22 EP disclosed
EP-0440923-B1 Polyolefin resin compositions and process for producing same SUMITOMO CHEMICAL CO (JP) 1997-06-04 EP disclosed
WO-1996020832-A1 COATED SHEET MATERIAL AND METHOD A*WARE TECHNOLOGIES, L.C. (US) 1996-07-11 WO disclosed
EP-0532893-A2 Depolymerization of polymers and their use in thermoset compositions and composites HERCULES INCORPORATED (US) 1993-03-24 EP disclosed
US-4913897-A SPREADING LAYER OF DISSOLVED POLYMER ONTO SKIN, DRYING TO FORM FILM, EVAPORATING BIO-PRODUCTS, INC. (US) 1990-04-03 US disclosed
US-4631188-A Injectable physiologically-acceptable polymeric composition S.K.Y. Polymers, Ltd. (Kingston Technologies) (US) 1986-12-23 US disclosed