Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 8/20 | 0.34 |
| ▸ | PARP1 | P09874 | 3/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HTR3B | O95264 | 1/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9485272 | 1.00 | MAPK1 (0.51) | MAPK1SMN1; SMN2L3MBTL1ACHEPARP1 | |
| SCHEMBL9444177 | 0.81 | L3MBTL1 (0.57) | MAPK1SMN1; SMN2L3MBTL1ACHECHRM3 | |
| Hydrochloric Acid SCHEMBL9444156 | 0.81 | L3MBTL1 (0.56) | MAPK1SMN1; SMN2L3MBTL1ACHECHRM3 | |
| SCHEMBL9631976 | 0.78 | MAPK1 (0.73) | MAPK1SMN1; SMN2L3MBTL1ACHECHRM3 | |
| SCHEMBL9485311 | 0.76 | MAPK1 (0.46) | MAPK1SMN1; SMN2L3MBTL1ACHECHRM3 | |
| SCHEMBL9486504 | 0.75 | L3MBTL1 (0.49) | MAPK1SMN1; SMN2L3MBTL1ACHECHRM3 | |
| SCHEMBL9492935 | 0.74 | MAPK1 (0.44) | MAPK1SMN1; SMN2L3MBTL1ACHEPARP1 | |
| Hydrochloric Acid SCHEMBL9853409 | 0.73 | MAPK1 (0.51) | MAPK1SMN1; SMN2L3MBTL1ACHEMEN1 | |
| SCHEMBL13921299 | 0.69 | MAPK1 (0.82) | MAPK1SMN1; SMN2L3MBTL1ACHECHRM3 | |
| SCHEMBL9486682 | 0.68 | L3MBTL1 (0.43) | MAPK1SMN1; SMN2L3MBTL1ACHEPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5227388-A | Analgesics | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-07-13 | — | — | US | disclosed |