Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 4/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13921299 | 0.85 | MAPK1 (0.82) | MAPK1SMN1; SMN2L3MBTL1ACHECHRM2 | |
| SCHEMBL7819239 | 0.83 | MAPK1 (0.49) | MAPK1SMN1; SMN2L3MBTL1PDK2SLC6A2 | |
| SCHEMBL9444177 | 0.80 | L3MBTL1 (0.57) | MAPK1SMN1; SMN2L3MBTL1POLBPDK2 | |
| Hydrochloric Acid SCHEMBL9444156 | 0.79 | L3MBTL1 (0.56) | MAPK1SMN1; SMN2L3MBTL1POLBPDK2 | |
| Hydrochloric Acid SCHEMBL9853409 | 0.78 | MAPK1 (0.51) | MAPK1SMN1; SMN2L3MBTL1POLBACHE | |
| SCHEMBL9444101 | 0.78 | MAPK1 (0.51) | MAPK1SMN1; SMN2L3MBTL1PDK2SLC6A4 | |
| SCHEMBL9485272 | 0.78 | MAPK1 (0.51) | MAPK1SMN1; SMN2L3MBTL1PDK2SLC6A4 | |
| SCHEMBL7312265 | 0.78 | PDK2 (0.45) | MAPK1SMN1; SMN2L3MBTL1PDK2KMT2A | |
| SCHEMBL7295187 | 0.76 | L3MBTL1 (0.70) | MAPK1SMN1; SMN2L3MBTL1CHRM2CHRM4 | |
| SCHEMBL9485683 | 0.75 | L3MBTL1 (0.68) | MAPK1SMN1; SMN2L3MBTL1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079249-A | Serotine antagonists at 5-HT2 level, antiallergens, antihistamines | ADIR ET COMPAGNIE (FR) | 1992-01-07 | — | — | US | disclosed |
| US-5071847-A | BIS (ARYL) ALKENE COMPOUNDS OF HOMOPIPERIDINES USEFUL AS SEROTONIN-ANTAGONISTS | ADIR ET COMPAGNIE (FR) | 1991-12-10 | — | — | US | disclosed |
| US-5028607-A | Antiserotonine agents | ADIR ET COMPAGNIE (FR) | 1991-07-02 | — | — | US | disclosed |