Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 5/20 | 0.63 |
| ▸ | CYP4A11 | Q02928 | 5/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10508352 | 0.86 | CYP4F2 (0.49) | CYP4F2CYP4A11MAPTRAB9AALDH1A1 | |
| SCHEMBL27695146 | 0.86 | CYP4F2 (0.58) | CYP4F2CYP4A11MAPTMEP1BCA2 | |
| SCHEMBL11638638 | 0.83 | CYP4F2 (0.69) | CYP4F2CYP4A11MAPTMEP1BCA2 | |
| SCHEMBL4339720 | 0.83 | CYP4F2 (0.54) | CYP4F2CYP4A11MAPTRAB9AALDH1A1 | |
| SCHEMBL2571306 | 0.83 | CYP4F2 (0.54) | CYP4F2CYP4A11MAPTRAB9AALDH1A1 | |
| SCHEMBL31455578 | 0.83 | CYP4F2 (0.54) | CYP4F2CYP4A11MAPTRAB9AALDH1A1 | |
| SCHEMBL4425984 | 0.82 | CYP4F2 (0.64) | CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL8949618 | 0.82 | CA12 (0.52) | CYP4F2CYP4A11MAPTCA2NPC1 | |
| SCHEMBL27676657 | 0.82 | CYP4F2 (0.60) | CYP4F2CYP4A11MAPTMEP1BCA2 | |
| SCHEMBL13104077 | 0.81 | CYP4F2 (0.58) | CYP4F2CYP4A11MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5273999-A | A 4-keto-boroalkyleneoxychroman or 2,3-dihydrobenzofuran derivative | HOFFMANN-LA ROCHE INC. (US) | 1993-12-28 | — | — | US | disclosed |