Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9444564 | 0.86 | CYP4F2 (0.63) | CYP4F2CYP4A11MAPTALDH1A1RAB9A | |
| SCHEMBL2571306 | 0.83 | CYP4F2 (0.54) | CYP4F2CYP4A11L3MBTL1MAPTALDH1A1 | |
| SCHEMBL31455578 | 0.83 | CYP4F2 (0.54) | CYP4F2CYP4A11L3MBTL1MAPTALDH1A1 | |
| SCHEMBL4339720 | 0.83 | CYP4F2 (0.54) | CYP4F2CYP4A11L3MBTL1MAPTALDH1A1 | |
| SCHEMBL4425984 | 0.82 | CYP4F2 (0.64) | CYP4F2CYP4A11ALDH1A1TDP1SYK | |
| SCHEMBL879289 | 0.81 | CYP4F2 (0.58) | CYP4F2CYP4A11L3MBTL1TDP1RAB9A | |
| SCHEMBL30540945 | 0.81 | FFAR1 (0.55) | CYP4F2CYP4A11TDP1SYK | |
| Ethyl Propionate SCHEMBL8595998 | 0.78 | F10 (0.44) | CYP4F2CYP4A11L3MBTL1MAPTALDH1A1 | |
| SCHEMBL13104077 | 0.78 | CYP4F2 (0.58) | CYP4F2CYP4A11L3MBTL1MAPTALDH1A1 | |
| SCHEMBL363982 | 0.77 | CYP4F2 (0.77) | CYP4F2CYP4A11L3MBTL1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0085959-B1 | AROMATIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1989-04-19 | — | — | EP | disclosed |
| EP-0249950-A1 | Aromatic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1987-12-23 | — | — | EP | disclosed |
| US-4564685-A | ANTIHISTAMINES | BURROUGHS WELLCOME CO., A CORP OF NC. | 1986-01-14 | — | — | US | disclosed |
| EP-0085959-A2 | Aromatic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1983-08-17 | — | — | EP | disclosed |