SCHEMBL4339720

SCHEMBL4339720

CCOC(=O)CCc1cccc(C(C)=O)c1

nearest known ligand 0.54

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 4/20 0.54
CYP4A11 Q02928 4/20 0.54
MAPT P10636 2/20 0.49
KMT2A Q03164 2/20 0.48
TDP1 Q9NUW8 3/20 0.47
F2 P00734 1/20 0.46
F10 P00742 1/20 0.46
ALDH1A1 P00352 2/20 0.46
GAA P10253 1/20 0.46
MAOB P27338 2/20 0.46
PPARG P37231 1/20 0.45
PPARA Q07869 1/20 0.45
RAB9A P51151 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
CYP4Z1 Q86W10 1/20 0.44
HPGD P15428 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2571306 0.88 CYP4F2 (0.54) CYP4F2CYP4A11MAPTTDP1F2
SCHEMBL31455578 0.88 CYP4F2 (0.54) CYP4F2CYP4A11MAPTTDP1F2
SCHEMBL4425984 0.87 CYP4F2 (0.64) CYP4F2CYP4A11TDP1ALDH1A1GAA
SCHEMBL27399582 0.84 CYP4F2 (0.54) CYP4F2CYP4A11KMT2AF2F10
SCHEMBL16369473 0.84 CYP4F2 (0.49) CYP4F2CYP4A11KMT2AF10ALDH1A1
SCHEMBL10508352 0.83 CYP4F2 (0.49) CYP4F2CYP4A11MAPTTDP1F2
SCHEMBL9444564 0.83 CYP4F2 (0.63) CYP4F2CYP4A11MAPTALDH1A1RAB9A
SCHEMBL13104077 0.83 CYP4F2 (0.58) CYP4F2CYP4A11MAPTTDP1ALDH1A1
SCHEMBL879289 0.83 CYP4F2 (0.58) CYP4F2CYP4A11KMT2ATDP1PPARG
SCHEMBL2745464 0.81 CYP4F2 (0.57) CYP4F2CYP4A11TDP1ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118201919-A Indole compounds and methods of use 健赞公司 2024-06-14 CN disclosed
CN-118026995-A Dihydrotriazole aromatization precursor and application thereof in deacylating and arylating reaction of ketone 国科大杭州高等研究院 2024-05-14 CN disclosed
US-7544835-B2 Carboxylic acid derivative and salt thereof EISAI R&D MANAGEMENT CO., LTD. (JP) 2009-06-09 US disclosed
US-20040102634-A1 Carboxylic acid derivative and salt thereof EISAI R&D MANAGEMENT CO., LTD. (JP) 2004-05-27 US disclosed
EP-1380562-A1 CARBOXYLIC ACID DERIVATIVE AND SALT THEREOF Eisai Co., Ltd. (JP) 2004-01-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040102634-A1 Carboxylic acid derivative and salt thereof GPR119, IRS1, SLC5A1 CYP4F2 792/4885CYP4A11 188/4885MAPT 4654/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.