SCHEMBL9445876

SCHEMBL9445876

Cc1ccc(S(=O)(=O)Nc2cc(S(=O)(=O)O)cc3c2C(=O)c2ccccc2C3=O)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGAM1 P18669 13/20 0.68
CDK2 P24941 1/20 0.58
MAPT P10636 3/20 0.56
LMNA P02545 3/20 0.56
ALDH1A1 P00352 2/20 0.56
USP2 O75604 1/20 0.56
POLB P06746 1/20 0.56
CYP2C9 P11712 1/20 0.56
CYP2C19 P33261 1/20 0.56
NOD2 Q9HC29 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
MAPK1 P28482 1/20 0.55
HTT P42858 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
KDM4E B2RXH2 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
CA12 O43570 1/20 0.51
CA2 P00918 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9355358 0.81 LMNA (0.69) PGAM1CDK2MAPTLMNAALDH1A1
SCHEMBL28732186 0.81 PGAM1 (1.00) PGAM1
SCHEMBL9178476 0.81 LMNA (0.73) PGAM1CDK2MAPTLMNAALDH1A1
SCHEMBL31037859 0.81 CDK2 (0.79) PGAM1CDK2MAPTLMNAALDH1A1
SCHEMBL9174847 0.81 CDK2 (0.79) PGAM1CDK2MAPTLMNAALDH1A1
SCHEMBL7538903 0.80 CDK2 (0.77) PGAM1CDK2MAPTLMNAALDH1A1
SCHEMBL9172475 0.77 LMNA (0.71) PGAM1CDK2MAPTLMNAALDH1A1
SCHEMBL9171170 0.76 PGAM1 (0.67) PGAM1CDK2MAPTLMNAALDH1A1
SCHEMBL28195405 0.76 P2RY4 (0.51) PGAM1MAPTLMNAALDH1A1L3MBTL1
SCHEMBL11782999 0.75 CDK2 (0.71) PGAM1CDK2MAPTLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0525073-A1 ANTHRAQUINONES AS INHIBITORS OF SULFIDE PRODUCTION FROM SULFATE-REDUCING BACTERIA. DU PONT (US) 1993-02-03 EP disclosed
WO-1991015954-A1 ANTHRAQUINONES AS INHIBITORS OF SULFIDE PRODUCTION FROM SULFATE-REDUCING BACTERIA E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-10-31 WO disclosed