Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9445916 | 0.80 | PPARD (0.48) | ALDH1A1HSD17B10PPARDTSHRCA12 | |
| SCHEMBL9445918 | 0.76 | PPARD (0.44) | ALDH1A1HSD17B10PPARDTSHRCA12 | |
| SCHEMBL9445991 | 0.75 | PPARD (0.43) | ALDH1A1HSD17B10PPARDTSHRCA12 | |
| SCHEMBL9674749 | 0.71 | PPARD (0.54) | ALDH1A1HSD17B10PPARDTSHR | |
| SCHEMBL13529619 | 0.70 | TSHR (0.48) | ALDH1A1HSD17B10PPARDTSHR | |
| SCHEMBL8761436 | 0.69 | TSHR (0.34) | HSD17B10TSHR | |
| SCHEMBL9445927 | 0.68 | ALDH1A1 (0.35) | ALDH1A1HSD17B10TSHRCA12CA1 | |
| SCHEMBL9445929 | 0.68 | ALDH1A1 (0.35) | ALDH1A1HSD17B10TSHRCA12CA1 | |
| SCHEMBL2361759 | 0.68 | TSHR (0.50) | ALDH1A1HSD17B10TSHRCA12CA2 | |
| SCHEMBL3165953 | 0.68 | TSHR (0.44) | ALDH1A1HSD17B10PPARDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5179085-A | Cerebrovascular disorders | WARNER-LAMBERT COMPANY (US) | 1993-01-12 | — | — | US | disclosed |