Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 7/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | PGK1 | P00558 | 2/20 | 0.43 |
| ▸ | PGK2 | P07205 | 2/20 | 0.43 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3390400 | 0.82 | PGK1 (0.52) | PGK1PGK2ACP3ACHE | |
| SCHEMBL9445936 | 0.82 | PGK1 (0.45) | PGK1PGK2ACP3 | |
| SCHEMBL2031911 | 0.78 | TSHR (0.43) | PGK1PGK2 | |
| SCHEMBL9445996 | 0.78 | PGK1 (0.42) | DRD2PGK1PGK2ACP3 | |
| SCHEMBL27887459 | 0.75 | PGK1 (0.41) | PGK1PGK2ACP3ACHE | |
| SCHEMBL29024551 | 0.75 | PGK1 (0.53) | PGK1PGK2ACP3 | |
| SCHEMBL1362338 | 0.75 | MEN1 (0.41) | PGK1PGK2 | |
| SCHEMBL1338013 | 0.75 | PGK1 (0.44) | PGK1PGK2ACP3KIF11 | |
| SCHEMBL24351980 | 0.74 | TAAR1 (0.61) | TAAR1DRD2DRD1NOS1KIF11 | |
| SCHEMBL1556937 | 0.73 | PTPN1 (0.52) | PGK1PGK2KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5179085-A | Cerebrovascular disorders | WARNER-LAMBERT COMPANY (US) | 1993-01-12 | — | — | US | disclosed |