Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.30 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.30 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.30 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9445927 | 1.00 | ALDH1A1 (0.35) | ALDH1A1HSD17B10CA12CA1CA2 | |
| SCHEMBL9445916 | 0.75 | PPARD (0.48) | ALDH1A1HSD17B10CA12CA1CA2 | |
| SCHEMBL14457784 | 0.72 | AOX1 (0.39) | ALDH1A1LPAR3TSHR | |
| SCHEMBL9569608 | 0.72 | PPARD (0.43) | CA1CA9LPAR3LPAR1LPAR2 | |
| SCHEMBL9569613 | 0.72 | PPARD (0.43) | CA1CA9LPAR3LPAR1LPAR2 | |
| SCHEMBL31519202 | 0.72 | TSHR (0.40) | ALDH1A1LPAR3LPAR1LPAR2TSHR | |
| SCHEMBL9445918 | 0.71 | PPARD (0.44) | ALDH1A1HSD17B10CA12CA1CA2 | |
| SCHEMBL2363295 | 0.71 | LPAR3 (0.55) | ALDH1A1LPAR3LPAR1LPAR2TSHR | |
| SCHEMBL2363294 | 0.71 | LPAR3 (0.55) | ALDH1A1LPAR3LPAR1LPAR2TSHR | |
| SCHEMBL9445991 | 0.70 | PPARD (0.43) | ALDH1A1HSD17B10CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5179085-A | Cerebrovascular disorders | WARNER-LAMBERT COMPANY (US) | 1993-01-12 | — | — | US | disclosed |