Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | ACP3 | P15309 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9446007 | 1.00 | NR4A2 (0.42) | NR4A2ACP3TSHRCD274MAPK1 | |
| SCHEMBL5035394 | 0.80 | ACP3 (0.45) | ACP3TSHRMAPK1 | |
| SCHEMBL29242881 | 0.78 | POLB (0.58) | NR4A2TSHRMAPK1KDM4E | |
| SCHEMBL6243532 | 0.78 | POLB (0.58) | NR4A2TSHRMAPK1KDM4E | |
| SCHEMBL6239035 | 0.78 | KDM4E (0.60) | NR4A2CD274KDM4E | |
| SCHEMBL7139605 | 0.78 | KDM4E (0.60) | NR4A2CD274KDM4E | |
| SCHEMBL6245180 | 0.78 | POLB (0.58) | NR4A2TSHRMAPK1KDM4E | |
| SCHEMBL7144643 | 0.78 | KDM4E (0.60) | NR4A2CD274KDM4E | |
| SCHEMBL9445919 | 0.77 | MEP1B (0.49) | ACP3CD274 | |
| SCHEMBL9445921 | 0.77 | MEP1B (0.49) | ACP3CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5179085-A | Cerebrovascular disorders | WARNER-LAMBERT COMPANY (US) | 1993-01-12 | — | — | US | disclosed |