Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.43 |
| ▸ | GPX4 | P36969 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.37 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11785353 | 0.90 | TP53 (0.47) | ALDH1A1RAB9ATP53NPC1PAX8 | |
| SCHEMBL11786816 | 0.88 | GPX4 (0.54) | ALDH1A1RAB9ATP53NPC1PAX8 | |
| SCHEMBL19129471 | 0.86 | TP53 (0.42) | ALDH1A1RAB9ATP53NPC1PAX8 | |
| SCHEMBL1802310 | 0.86 | TP53 (0.45) | ALDH1A1RAB9ATP53NPC1PAX8 | |
| SCHEMBL10909573 | 0.85 | TP53 (0.44) | ALDH1A1RAB9ATP53NPC1PAX8 | |
| SCHEMBL10661624 | 0.81 | TAAR1 (0.49) | ALDH1A1RAB9ANPC1PAX8SLC6A2 | |
| SCHEMBL11694481 | 0.78 | TP53 (0.41) | ALDH1A1RAB9ATP53NPC1PAX8 | |
| SCHEMBL10658926 | 0.78 | RAB9A (0.52) | ALDH1A1RAB9ATP53NPC1PAX8 | |
| SCHEMBL11880892 | 0.76 | TP53 (0.44) | ALDH1A1RAB9ATP53NPC1PAX8 | |
| SCHEMBL11748273 | 0.75 | TP53 (0.42) | ALDH1A1RAB9ATP53NPC1PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250420-A | Using an electron carrier | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1993-10-05 | — | — | US | disclosed |
| EP-0285998-B1 | METHOD AND REAGENT FOR DETERMINATION OF DEHYDROGENASE OR ITS SUBSTRATE | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1993-08-04 | — | — | EP | disclosed |
| EP-0285998-A2 | Method and reagent for determination of dehydrogenase or its substrate | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1988-10-12 | — | — | EP | disclosed |
| US-4251629-A | COLORIMETRY, USING 4-AMINOANTIPYRENE, N-SUBSTITUTED ANILINE, ACTIVATOR | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1981-02-17 | — | — | US | disclosed |
| US-4208502-A | Curable resin compositions | CELANESE CORPORATION (US) | 1980-06-17 | — | — | US | disclosed |
| US-4098918-A | METHOD OF POLYMERIZING NON-LINEAR URETHANE DIACRYLATES USING RADIATION | PPG INDUSTRIES, INC. (US) | 1978-07-04 | — | — | US | disclosed |
| US-4064286-A | RESISTANCE TO COLOR BLEACHING, CHALKING, IMPROVED GLOSS RETENTION | PPG INDUSTRIES, INC. (US) | 1977-12-20 | — | — | US | disclosed |
| US-4017649-A | Radiation-sensitive compounds and methods of using same | PPG INDUSTRIES, INC. (US) | 1977-04-12 | — | — | US | disclosed |
| US-3988272-A | FROM ETHYLENICALLY UNSATURATED COMPOUNDS WITH N-HYDROXYALKYL AND PHENYL-SUBSTITUTED AMINE, COBALT SALTS AND PEROXY FREE RADICAL CATALYSTS | ASHLAND OIL, INC. (US) | 1976-10-26 | — | — | US | disclosed |
| US-3979426-A | Radiation-sensitive diacrylates | PPG INDUSTRIES, INC. (US) | 1976-09-07 | — | — | US | disclosed |
| US-3950287-A | CURING, AMINES, FREE RADICAL CATALYSTS | ASHLAND OIL, INC. (US) | 1976-04-13 | — | — | US | disclosed |