Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20123234 | 0.79 | TDP1 (0.48) | MAPTALDH1A1KDM4EGAALMNA | |
| SCHEMBL27967338 | 0.77 | ALDH1A1 (0.40) | ALDH1A1KDM4EGAATDP1CYP3A4 | |
| SCHEMBL5270436 | 0.77 | CYP3A4 (0.40) | ALDH1A1KDM4EGAATDP1CYP3A4 | |
| SCHEMBL29727382 | 0.77 | TDP1 (0.58) | MAPTALDH1A1KDM4EGAALMNA | |
| SCHEMBL1961832 | 0.77 | TDP1 (0.58) | MAPTALDH1A1KDM4EGAALMNA | |
| SCHEMBL29421891 | 0.76 | EPHX2 (0.57) | MAPTTDP1EPHX2FYNCYP3A4 | |
| SCHEMBL4472439 | 0.76 | EPHX2 (0.57) | MAPTTDP1EPHX2FYNCYP3A4 | |
| SCHEMBL17368405 | 0.74 | TUBB4A (0.39) | MAPTALDH1A1KDM4EGAALMNA | |
| SCHEMBL3005373 | 0.73 | CYP3A4 (0.40) | ALDH1A1KDM4EGAATDP1CYP3A4 | |
| SCHEMBL27773010 | 0.73 | CYP3A4 (0.40) | ALDH1A1KDM4EGAATDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254590-A | Enzyme inhibitors, anticholesterol, treatment of atheroscherosis, dylipidemias | ADIR ET COMPAGNIE (FR) | 1993-10-19 | — | — | US | disclosed |
| EP-0508842-A1 | Aminoacylphenol derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-10-14 | — | — | EP | disclosed |