Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.42 |
| ▸ | WDR5 | P61964 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28214627 | 0.94 | PTPN11 (0.54) | CNR2PTPN11S1PR3PTPN1PTPN6 | |
| SCHEMBL28886160 | 0.92 | CNR2 (0.43) | CNR2PTPN11S1PR3PTPN1PTPN6 | |
| SCHEMBL12516907 | 0.87 | CNR2 (0.49) | CNR2PTPN11S1PR3PTPN1PTPN6 | |
| SCHEMBL8091128 | 0.87 | CNR2 (0.53) | CNR2PTPN11S1PR3PTPN1PTPN6 | |
| SCHEMBL14699866 | 0.83 | CNR2 (0.52) | CNR2PTPN11S1PR3PTPN1PTPN6 | |
| SCHEMBL8629610 | 0.82 | LMNA (0.50) | TSHR | |
| SCHEMBL12697313 | 0.81 | TSHR (0.51) | CNR2PTPN11TP53TSHRRARA | |
| SCHEMBL28359092 | 0.81 | PTPN11 (0.57) | CNR2PTPN11S1PR3PTPN1PTPN6 | |
| SCHEMBL27845339 | 0.81 | PTPN11 (0.47) | PTPN11S1PR3WDR5 | |
| SCHEMBL7190808 | 0.81 | PTPN11 (0.41) | CNR2PTPN11S1PR3PTPN1PTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5206011-A | Two different film forming polymers, plasticizer, organoclay thixotropic agent, pigment, wetting agent, solvent system including acetone | AMALIA INC. (US) | 1993-04-27 | — | — | US | disclosed |
| EP-0507888-A4 | QUICK-DRYING NAIL ENAMEL COMPOSITIONS | — | 1993-04-14 | — | — | EP | disclosed |
| EP-0507888-A1 | QUICK-DRYING NAIL ENAMEL COMPOSITIONS | AMALIA, INC. (US) | 1992-10-14 | — | — | EP | disclosed |
| WO-1992010160-A1 | QUICK-DRYING CREME PIGMENTED NAIL ENAMEL COMPOSITIONS AND METHOD FOR COATING A SURFACE | AMALIA, INC. (US) | 1992-06-25 | — | — | WO | disclosed |
| WO-1991008731-A1 | QUICK-DRYING NAIL ENAMEL COMPOSITIONS | AMALIA, INC. (US) | 1991-06-27 | — | — | WO | disclosed |