Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | FAAH | O00519 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.50 |
| ▸ | PLA2G4A | P47712 | 5/20 | 0.48 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9446399 | 0.86 | FAAH (0.54) | MEN1FAAHMAPK1KMT2ALPAR3 | |
| SCHEMBL9446398 | 0.82 | PLA2G4A (0.50) | MEN1FAAHMAPK1KMT2ALPAR3 | |
| SCHEMBL9446396 | 0.81 | MEN1 (0.49) | MEN1FAAHMAPK1KMT2ALPAR3 | |
| SCHEMBL28058368 | 0.77 | MEN1 (0.53) | MEN1FAAHMAPK1KMT2ALPAR3 | |
| SCHEMBL15709298 | 0.77 | MEN1 (0.53) | MEN1FAAHMAPK1KMT2ALPAR3 | |
| SCHEMBL2441860 | 0.75 | FAAH (0.51) | MEN1FAAHMAPK1KMT2ALPAR3 | |
| SCHEMBL6313266 | 0.73 | FAAH (0.66) | MEN1FAAHMAPK1KMT2ADNM1 | |
| SCHEMBL277126 | 0.73 | FAAH (1.00) | MEN1FAAHMAPK1KMT2ADNM1 | |
| SCHEMBL20143550 | 0.73 | FAAH (1.00) | MEN1FAAHMAPK1KMT2ADNM1 | |
| SCHEMBL4023787 | 0.73 | FAAH (1.00) | MEN1FAAHMAPK1KMT2ADNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533825-A4 | ETHER LIPID-NUCLEOSIDE COVALENT CONJUGATES | — | 1993-06-02 | — | — | EP | disclosed |
| EP-0533825-A1 | ETHER LIPID-NUCLEOSIDE COVALENT CONJUGATES. | UNIV WAKE FOREST (US) | 1993-03-31 | — | — | EP | disclosed |