Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | KIF20A | O95235 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.42 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9446456 | 1.00 | MAPT (0.48) | MAPTKDM4ENPSR1MEN1KMT2A | |
| SCHEMBL987696 | 0.80 | MAPT (0.77) | MAPTKDM4ENPSR1MEN1KMT2A | |
| SCHEMBL9015118 | 0.77 | MCL1 (0.52) | MAPTKDM4ENPSR1MEN1KMT2A | |
| SCHEMBL2000510 | 0.77 | MCL1 (0.52) | MAPTKDM4ENPSR1MEN1KMT2A | |
| SCHEMBL28668178 | 0.77 | MAPT (0.46) | MAPTKDM4ENPSR1MEN1KMT2A | |
| SCHEMBL11761824 | 0.77 | GABRA1 (0.58) | MAPTKDM4ENPSR1MEN1KMT2A | |
| SCHEMBL11761830 | 0.77 | GABRA1 (0.58) | MAPTKDM4ENPSR1MEN1KMT2A | |
| SCHEMBL1503839 | 0.77 | TRPA1 (0.52) | ALDH1A1LMNATRPA1HTTFBP1 | |
| SCHEMBL28692843 | 0.75 | MAPT (0.45) | MAPTKDM4ENPSR1MEN1KMT2A | |
| SCHEMBL13485321 | 0.75 | ESR1 (0.69) | MAPTKDM4ENPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5233052-A | Insecticidal and acaricidal diarylpyrrolecarbonitrile and diarylnitropyrrole compounds | AMERICAN CYANAMID COMPANY (US) | 1993-08-03 | — | — | US | disclosed |
| US-5180734-A | INSECTICIDAL AND ACARICIDAL DIARYLPYRROLECARBONITRILE AND DIARYLNITROPYRROLE COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 1993-01-19 | — | — | US | disclosed |