Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 8/20 | 0.66 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.66 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | THPO | P40225 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9446982 | 0.88 | AR (0.64) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL10655893 | 0.82 | CYSLTR1 (0.70) | CYSLTR1CYSLTR2F2MAPTKDM4E | |
| SCHEMBL9447068 | 0.82 | SLC40A1 (0.48) | CYSLTR1CYSLTR2MAPTMEN1ALDH1A1 | |
| SCHEMBL10755026 | 0.81 | CYSLTR1 (0.72) | CYSLTR1CYSLTR2MAPTKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL9447146 | 0.81 | CYSLTR1 (0.69) | CYSLTR1CYSLTR2F2MAPTKDM4E | |
| SCHEMBL9447225 | 0.80 | CYSLTR1 (0.67) | CYSLTR1CYSLTR2MAPTKDM4EMEN1 | |
| Ritolukast SCHEMBL38043 | 0.80 | CYSLTR1 (1.00) | CYSLTR1CYSLTR2MAPTKDM4EMEN1 | |
| SCHEMBL9447118 | 0.77 | CYSLTR1 (0.66) | CYSLTR1CYSLTR2MAPTKDM4EMEN1 | |
| SCHEMBL10510977 | 0.77 | CYSLTR1 (0.69) | CYSLTR1CYSLTR2TP53CYP1A2CYP3A4 | |
| SCHEMBL9865792 | 0.77 | CYSLTR1 (0.56) | CYSLTR1CYSLTR2MAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5202336-A | Lipoxygenase inhibitors | BAYER AKTIENGESELLSCHAFT (DE) | 1993-04-13 | — | — | US | disclosed |
| US-5093340-A | Lipoxygenase enzyme inhibitors, antithrombolytic agents | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-03 | — | — | US | disclosed |
| US-5070096-A | ANTICOAGULANTS, LIPOXYGENASE INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-12-03 | — | — | US | disclosed |
| EP-0261539-A2 | Substituted phenyl-sulphon amides | BAYER AG (DE) | 1988-03-30 | — | — | EP | disclosed |