Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.64 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.55 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.55 |
| ▸ | PGR | P06401 | 2/20 | 0.54 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.54 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.53 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.51 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9446969 | 0.88 | CYSLTR1 (0.66) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL10690965 | 0.83 | CYSLTR1 (0.76) | CYSLTR1CYSLTR2PDE10AGPBAR1ALOX5AP | |
| SCHEMBL9447068 | 0.82 | SLC40A1 (0.48) | CYSLTR1CYSLTR2ADAMTS4 | |
| SCHEMBL9446949 | 0.81 | CYSLTR1 (0.54) | CYSLTR1CYSLTR2ADAMTS4PDE10AGPBAR1 | |
| SCHEMBL9446976 | 0.79 | AR (0.59) | ARCYSLTR1CYSLTR2PGRPDE10A | |
| SCHEMBL9447007 | 0.79 | CYSLTR1 (0.54) | ARCYSLTR1CYSLTR2ADAMTS4PDE10A | |
| SCHEMBL9469819 | 0.76 | CYSLTR1 (0.57) | CYSLTR1CYSLTR2PDE10AGPBAR1ALOX5AP | |
| SCHEMBL9447067 | 0.76 | AR (0.64) | ARCYSLTR1CYSLTR2PDE10AGPBAR1 | |
| SCHEMBL9876648 | 0.75 | CYSLTR2 (0.60) | CYSLTR1CYSLTR2ADAMTS4PDE10AGPBAR1 | |
| SCHEMBL8645017 | 0.75 | CYSLTR1 (0.70) | CYSLTR1CYSLTR2PDE10AGPBAR1ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5202336-A | Lipoxygenase inhibitors | BAYER AKTIENGESELLSCHAFT (DE) | 1993-04-13 | — | — | US | disclosed |
| US-5093340-A | Lipoxygenase enzyme inhibitors, antithrombolytic agents | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-03 | — | — | US | disclosed |
| US-5070096-A | ANTICOAGULANTS, LIPOXYGENASE INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-12-03 | — | — | US | disclosed |
| EP-0261539-A2 | Substituted phenyl-sulphon amides | BAYER AG (DE) | 1988-03-30 | — | — | EP | disclosed |