Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.53 |
| ▸ | CKS1B | P61024 | 2/20 | 0.52 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.52 |
| ▸ | SLC40A1 | Q9NP59 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9447198 | 0.86 | KMT2A (0.61) | KMT2AALDH1A1POLBL3MBTL1MEN1 | |
| SCHEMBL9800660 | 0.84 | CKS1B (0.58) | KMT2AALDH1A1POLBL3MBTL1MEN1 | |
| SCHEMBL21812550 | 0.80 | CKS1B (0.70) | KMT2AALDH1A1POLBMEN1MAPT | |
| SCHEMBL9446974 | 0.79 | SLC40A1 (0.60) | KMT2AALDH1A1MEN1MAPTGAA | |
| SCHEMBL9446988 | 0.78 | AR (0.48) | ALDH1A1MAPTGAACKS1BSKP2 | |
| SCHEMBL9446946 | 0.78 | PGR (0.62) | KMT2AALDH1A1POLBL3MBTL1MEN1 | |
| SCHEMBL9447120 | 0.78 | PGR (0.62) | KMT2AALDH1A1POLBL3MBTL1MEN1 | |
| SCHEMBL9446984 | 0.77 | MEN1 (0.71) | KMT2AALDH1A1MEN1MAPTGAA | |
| SCHEMBL9446952 | 0.76 | PGR (0.54) | KMT2AALDH1A1POLBL3MBTL1MEN1 | |
| SCHEMBL9447008 | 0.76 | GLO1 (0.62) | KMT2AALDH1A1L3MBTL1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5202336-A | Lipoxygenase inhibitors | BAYER AKTIENGESELLSCHAFT (DE) | 1993-04-13 | — | — | US | disclosed |
| US-5093340-A | Lipoxygenase enzyme inhibitors, antithrombolytic agents | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-03 | — | — | US | disclosed |
| US-5070096-A | ANTICOAGULANTS, LIPOXYGENASE INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-12-03 | — | — | US | disclosed |
| EP-0261539-B1 | SUBSTITUTED PHENYL-SULPHON AMIDES | BAYER AG (DE) | 1991-03-06 | — | — | EP | disclosed |