Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.54 |
| ▸ | CLK1 | P49759 | 1/20 | 0.53 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.52 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.44 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.44 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10655893 | 0.85 | CYSLTR1 (0.70) | CYSLTR2CYSLTR1MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL9447146 | 0.85 | CYSLTR1 (0.69) | CYSLTR2CYSLTR1MEN1KMT2ALMNA | |
| SCHEMBL9446976 | 0.84 | AR (0.59) | SLC40A1CLK1CYSLTR2CYSLTR1MEN1 | |
| SCHEMBL9447068 | 0.79 | SLC40A1 (0.48) | SLC40A1CYSLTR2CYSLTR1MEN1KMT2A | |
| SCHEMBL9446954 | 0.76 | SLC40A1 (0.70) | SLC40A1CLK1MEN1KMT2AGAA | |
| SCHEMBL9447092 | 0.75 | SLC40A1 (0.76) | SLC40A1CLK1MEN1KMT2AGAA | |
| SCHEMBL7592771 | 0.74 | MEN1 (0.74) | SLC40A1CLK1MEN1KMT2AGAA | |
| SCHEMBL10650394 | 0.74 | SLC40A1 (0.61) | SLC40A1CLK1MEN1KMT2AGAA | |
| SCHEMBL10543748 | 0.74 | CYSLTR1 (0.64) | CYSLTR2CYSLTR1 | |
| SCHEMBL7572994 | 0.73 | SLC40A1 (0.66) | SLC40A1CLK1MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5202336-A | Lipoxygenase inhibitors | BAYER AKTIENGESELLSCHAFT (DE) | 1993-04-13 | — | — | US | disclosed |
| US-5093340-A | Lipoxygenase enzyme inhibitors, antithrombolytic agents | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-03 | — | — | US | disclosed |
| US-5070096-A | ANTICOAGULANTS, LIPOXYGENASE INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-12-03 | — | — | US | disclosed |