Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | KDM6A | O15550 | 1/20 | 0.63 |
| ▸ | KDM4A | O75164 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | KDM5C | P41229 | 1/20 | 0.63 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.63 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.63 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | COMT | P21964 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 3/20 | 0.36 |
| ▸ | MGLL | Q99685 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Deferiprone SCHEMBL20775057 | 0.79 | KDM4E (1.00) | KDM4EKDM6AKDM4ACYP2C9CYP2C19 | |
| Deferiprone SCHEMBL94474 | 0.79 | KDM4E (1.00) | KDM4EKDM6AKDM4ACYP2C9CYP2C19 | |
| Deferiprone SCHEMBL10464107 | 0.78 | KDM4E (0.96) | KDM4EKDM6AKDM4ACYP2C9CYP2C19 | |
| Deferiprone SCHEMBL692741 | 0.78 | KDM4E (0.96) | KDM4EKDM6AKDM4ACYP2C9CYP2C19 | |
| SCHEMBL15846673 | 0.72 | FAAH (0.45) | ALDH1A1LMNAFAAHMGLLCYP24A1 | |
| SCHEMBL1325 | 0.72 | FAAH (0.45) | ALDH1A1LMNAFAAHMGLLCYP24A1 | |
| SCHEMBL2194853 | 0.70 | FAAH (0.44) | ALDH1A1LMNAFAAHMGLLCYP24A1 | |
| SCHEMBL10814524 | 0.70 | FAAH (0.44) | ALDH1A1LMNAFAAHMGLLCYP24A1 | |
| Hydrogen Sulfide SCHEMBL10814521 | 0.70 | FAAH (0.44) | ALDH1A1LMNAFAAHMGLLCYP24A1 | |
| Phosphine SCHEMBL31680518 | 0.70 | FAAH (0.44) | ALDH1A1LMNAFAAHMGLLCYP24A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5487884-A | CYTOPROTECTIVE AGENTS BY RADIATION RESISTANCE TO PREVENT SKIN CANCER AND PREMATURE AGING | THE PROCTER & GAMBLE COMPANY (US) | 1996-01-30 | — | — | US | disclosed |