Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.51 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.45 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.45 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | PLAU | P00749 | 2/20 | 0.39 |
| ▸ | CFD | P00746 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | F11 | P03951 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.39 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL906709 | 0.80 | CXCL8 (0.57) | CHRM1CXCL8LTB4RLTB4R2CAMK2A | |
| SCHEMBL9051204 | 0.78 | CYP1A2 (0.39) | L3MBTL1 | |
| SCHEMBL11097326 | 0.77 | CXCL8 (0.79) | CHRM1CXCL8CAMK2APLAUCFD | |
| SCHEMBL9165064 | 0.77 | PPARD (0.42) | IDO1PPARGPPARDPPARA | |
| SCHEMBL9051202 | 0.75 | EDNRB (0.55) | PPARGPPARA | |
| SCHEMBL7410289 | 0.72 | PPARG (0.50) | PPARGPPARAPLAU | |
| SCHEMBL4032382 | 0.72 | AKR1B1 (0.57) | CXCL8PPARGPPARA | |
| SCHEMBL1253400 | 0.71 | CXCL8 (0.66) | CHRM1CXCL8CAMK2AL3MBTL1 | |
| SCHEMBL11335218 | 0.70 | CXCL8 (0.59) | CHRM1CXCL8CAMK2AFFAR1 | |
| SCHEMBL2202797 | 0.70 | SLC6A2 (0.54) | PPARDSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5274104-A | N-substituted heterocyclic derivatives useful in the treatment of cardiovascular disorders | ELF SANOFI, A FRENCH CORP. (FR) | 1993-12-28 | — | — | US | disclosed |