Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 7/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 8/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | CALML3 | P27482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9447681 | 0.86 | F10 (0.53) | HTR6MAOAMAOBTSHRGRM2 | |
| SCHEMBL9447636 | 0.86 | F10 (0.53) | HTR6MAOAMAOBTSHRGRM2 | |
| SCHEMBL9635182 | 0.84 | GRM2 (0.46) | HTR6GRM2F10CALML3 | |
| SCHEMBL9447679 | 0.81 | HTR6 (0.43) | HTR6MAOAMAOBF10CALML3 | |
| SCHEMBL9447653 | 0.81 | HTR6 (0.43) | HTR6MAOAMAOBF10CALML3 | |
| SCHEMBL9447626 | 0.79 | MAOA (0.59) | MAOAMAOBF10CALML3 | |
| SCHEMBL9447667 | 0.79 | MAOA (0.59) | MAOAMAOBF10CALML3 | |
| SCHEMBL6192445 | 0.79 | MAOA (0.53) | HTR6MAOAMAOBGRM2CALML3 | |
| SCHEMBL6210718 | 0.79 | MAOA (0.53) | HTR6MAOAMAOBGRM2CALML3 | |
| SCHEMBL6210714 | 0.79 | MAOA (0.53) | HTR6MAOAMAOBGRM2CALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225565-A | Antibacterial 3-(fused-ring substituted)phenyl-5β-amidomethyloxazolidin-2-ones | THE UPJOHN COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| US-5182403-A | Bactericides, treatment of AIDS | THE UPJOHN COMPANY (US) | 1993-01-26 | — | — | US | disclosed |
| US-5164510-A | Bactericides | THE UPJOHN COMPANY (US) | 1992-11-17 | — | — | US | disclosed |
| EP-0434714-A1 | IN POSITION 3 SUBSTITUTED-5-BETA-AMIDOMETHYL-OXAZOLIDIN-2-ONES | THE UPJOHN COMPANY (US) | 1991-07-03 | — | — | EP | disclosed |
| WO-1990002744-A1 | IN POSITION 3 SUBSTITUTED-5-BETA-AMIDOMETHYL-OXAZOLIDIN-2-ONES | THE UPJOHN COMPANY (US) | 1990-03-22 | — | — | WO | disclosed |
| EP-0359418-A1 | 5'-Indolinyl-5beta-amidomethyloxazolidin-2-ones, 3-(fused-ring substituted)phenyl-5beta-amidomethyloxazolidin-2-ones and 3-(nitrogen substituted)phenyl-5beta-amidomethyloxazolidin-2-ones | THE UPJOHN COMPANY (US) | 1990-03-21 | — | — | EP | disclosed |