Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.43 |
| ▸ | F10 | P00742 | 9/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | CALML3 | P27482 | 1/20 | 0.39 |
| ▸ | SDHA | P31040 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9447653 | 1.00 | HTR6 (0.43) | HTR6F10MAOBLMNAMAOA | |
| SCHEMBL9447626 | 0.81 | MAOA (0.59) | F10MAOBLMNAMAOAPTGS1 | |
| SCHEMBL9447667 | 0.81 | MAOA (0.59) | F10MAOBLMNAMAOAPTGS1 | |
| SCHEMBL9447636 | 0.81 | F10 (0.53) | HTR6F10MAOBMAOACALML3 | |
| SCHEMBL9447681 | 0.81 | F10 (0.53) | HTR6F10MAOBMAOACALML3 | |
| SCHEMBL9447637 | 0.81 | HTR6 (0.47) | HTR6F10MAOBMAOACALML3 | |
| SCHEMBL9447659 | 0.80 | MAOB (0.61) | F10MAOBLMNAMAOAPTGS1 | |
| SCHEMBL9447651 | 0.80 | MAOB (0.61) | F10MAOBLMNAMAOAPTGS1 | |
| SCHEMBL9447632 | 0.80 | F10 (0.49) | F10MAOBLMNAMAOAPTGS1 | |
| SCHEMBL9447595 | 0.80 | F10 (0.49) | F10MAOBLMNAMAOAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225565-A | Antibacterial 3-(fused-ring substituted)phenyl-5β-amidomethyloxazolidin-2-ones | THE UPJOHN COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| US-5182403-A | Bactericides, treatment of AIDS | THE UPJOHN COMPANY (US) | 1993-01-26 | — | — | US | disclosed |
| US-5164510-A | Bactericides | THE UPJOHN COMPANY (US) | 1992-11-17 | — | — | US | disclosed |
| EP-0434714-A1 | IN POSITION 3 SUBSTITUTED-5-BETA-AMIDOMETHYL-OXAZOLIDIN-2-ONES | THE UPJOHN COMPANY (US) | 1991-07-03 | — | — | EP | disclosed |
| WO-1990002744-A1 | IN POSITION 3 SUBSTITUTED-5-BETA-AMIDOMETHYL-OXAZOLIDIN-2-ONES | THE UPJOHN COMPANY (US) | 1990-03-22 | — | — | WO | disclosed |
| EP-0359418-A1 | 5'-Indolinyl-5beta-amidomethyloxazolidin-2-ones, 3-(fused-ring substituted)phenyl-5beta-amidomethyloxazolidin-2-ones and 3-(nitrogen substituted)phenyl-5beta-amidomethyloxazolidin-2-ones | THE UPJOHN COMPANY (US) | 1990-03-21 | — | — | EP | disclosed |