Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6055808 | 0.70 | CYP19A1 (0.38) | CYP19A1NPC1ALDH1A1PLA2G1BNFKB1 | |
| SCHEMBL945667 | 0.70 | — | — | |
| SCHEMBL945379 | 0.67 | NPC1 (0.36) | CYP19A1NPC1ALDH1A1PLA2G1BNFKB1 | |
| SCHEMBL2873175 | 0.65 | NPC1 (0.46) | CYP19A1NPC1ALDH1A1PLA2G1BNFKB1 | |
| SCHEMBL945102 | 0.62 | — | — | |
| SCHEMBL946122 | 0.62 | — | — | |
| SCHEMBL944955 | 0.61 | KIF11 (0.30) | — | |
| SCHEMBL4651927 | 0.61 | CYP1A2 (0.33) | CYP19A1NPC1ALDH1A1PLA2G1BNFKB1 | |
| SCHEMBL1453750 | 0.61 | NFKB1 (0.36) | CYP19A1NPC1ALDH1A1PLA2G1BNFKB1 | |
| SCHEMBL1453531 | 0.61 | ALDH1A1 (0.36) | CYP19A1NPC1ALDH1A1PLA2G1BNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110003953-A1 | Carbon-Bridged Cyclopentadienyl-Fluorenyl Ligands | FINA TECHNOLOGY, INC. (US) | 2011-01-06 | — | — | US | disclosed |
| EP-1734059-A1 | Carbon-bridged cyclopentadienyl-fluorenyl ligands | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2006-12-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110003953-A1 | Carbon-Bridged Cyclopentadienyl-Fluorenyl Ligands | CCR3, CNOT9, MYCBP | CYP19A1 3604/4885NPC1 378/4885ALDH1A1 1588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.