Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11418809 | 0.86 | RAB9A (0.38) | RAB9AMMEAKR1B1LTA4H | |
| SCHEMBL1800549 | 0.76 | ACE (0.42) | LTA4H | |
| SCHEMBL8009656 | 0.73 | PSMB8 (0.30) | — | |
| SCHEMBL468592 | 0.72 | MEN1 (0.43) | RAB9ASMN1; SMN2 | |
| SCHEMBL5088219 | 0.66 | RAB9A (0.40) | RAB9AMMELTA4H | |
| Succinimide SCHEMBL27427653 | 0.62 | CRBN (0.55) | — | |
| SCHEMBL12858395 | 0.61 | RAB9A (1.00) | RAB9AMMELTA4HSMN1; SMN2 | |
| Succinimide SCHEMBL17844267 | 0.61 | CRBN (0.44) | — | |
| SCHEMBL5699653 | 0.59 | POLB (0.43) | SMN1; SMN2 | |
| SCHEMBL29511483 | 0.59 | POLB (0.43) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546156-A4 | ISOLATION AND CHARACTERIZATION OF A NOVEL PROTEASE FROM STREPTOMYCES LIVIDANS | — | 1993-06-30 | — | — | EP | disclosed |
| EP-0546156-A1 | ISOLATION AND CHARACTERIZATION OF A NOVEL PROTEASE FROM STREPTOMYCES LIVIDANS | AMGEN INC. (US) | 1993-06-16 | — | — | EP | disclosed |
| WO-1993000925-A1 | ISOLATION AND CHARACTERIZATION OF A NOVEL PROTEASE FROM STREPTOMYCES LIVIDANS | AMGEN INC. (US) | 1993-01-21 | — | — | WO | disclosed |