SCHEMBL1800549

SCHEMBL1800549

C[C@H](NC(=O)[C@]1(C)NC(=O)CCC1=O)C(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACE P12821 8/20 0.42
REN P00797 4/20 0.42
KDM4E B2RXH2 1/20 0.42
F2 P00734 1/20 0.42
LMNA P02545 1/20 0.42
LTA4H P09960 1/20 0.42
MAPT P10636 1/20 0.42
PEPD P12955 1/20 0.42
ALOX15 P16050 1/20 0.42
PTGS1 P23219 1/20 0.42
HTR2A P28223 1/20 0.42
PTGS2 P35354 1/20 0.42
HRH1 P35367 1/20 0.42
THPO P40225 1/20 0.42
PMP22 Q01453 1/20 0.42
HSD17B10 Q99714 1/20 0.42
ACE2 Q9BYF1 1/20 0.42
KMT2A Q03164 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
MEN1 O00255 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7624015 0.84 CMA1 (0.42) ACEREN
SCHEMBL4410753 0.82 ELANE (0.38) KMT2AMEN1
SCHEMBL8205946 0.81 ACE (0.50) ACEHSD17B10
SCHEMBL10895690 0.78 ELANE (0.42) KMT2AMEN1
SCHEMBL7641458 0.78 XIAP (0.44) ACE
SCHEMBL3314831 0.78 TACR1 (0.41) LMNAMAPTKMT2AMEN1
SCHEMBL535732 0.76 ACE (0.40) ACERENKDM4EF2LMNA
SCHEMBL9448797 0.76 RAB9A (0.44) LTA4H
SCHEMBL16021695 0.73 ACE (0.59) ACERENKDM4EF2LMNA
SCHEMBL11376449 0.72 PREP (0.62) ACERENKDM4EF2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2496596-A1 THERAPEUTIC PEPTIDES Lytix Biopharma AS (NO) 2012-09-12 EP disclosed
WO-2011051692-A1 THERAPEUTIC PEPTIDES LYTIX BIOPHARMA AS (NO) 2011-05-05 WO disclosed
EP-0925307-A4 ENZYME AND DNA SEQUENCE ENCODING SAME PHAIRSON MEDICAL INC (GB) 2002-10-16 EP disclosed
EP-0925307-A1 ENZYME AND DNA SEQUENCE ENCODING SAME Phairson Medical, Inc. (GB) 1999-06-30 EP disclosed
WO-1998008863-A1 ENZYME AND DNA SEQUENCE ENCODING SAME PHAIRSON MEDICAL, INC. (GB) 1998-03-05 WO disclosed