SCHEMBL8009656

SCHEMBL8009656

C[C@H](NC(=O)[C@]1(C)NC(=O)CCC1=O)C(=O)N[C@@H](C)C(=O)N([N+]=O)c1ccccc1

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PSMB8 P28062 1/20 0.30
PSMB9 P28065 1/20 0.30
PSMB5 P28074 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1965383 0.74 SLC1A2 (0.47)
SCHEMBL9448797 0.73 RAB9A (0.44)
SCHEMBL11418809 0.72 RAB9A (0.38)
SCHEMBL5793359 0.66 RAB9A (0.42)
SCHEMBL8330156 0.66 MEN1 (0.39)
SCHEMBL7375030 0.64 L3MBTL1 (0.40) PSMB8PSMB9PSMB5
SCHEMBL8351160 0.64 MMP1 (0.45) PSMB8PSMB9PSMB5
SCHEMBL1800549 0.61 ACE (0.42)
SCHEMBL18342512 0.61 ALDH1A1 (0.38)
SCHEMBL5676105 0.59 SLC7A5 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000032806-A1 METHOD FOR THE QUANTITATIVE DETERMINATION OF PROTEINASE INHIBITORS BRISTOW CINDY L (US) 2000-06-08 WO disclosed