Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 14/20 | 0.60 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9214803 | 0.90 | ALOX5 (0.48) | ALOX5S1PR1S1PR3 | |
| SCHEMBL9448945 | 0.86 | ALOX5 (0.61) | ALOX5ALOX12PTGS1PTGS2 | |
| SCHEMBL9448870 | 0.84 | ALOX5 (0.48) | ALOX5ALOX12PTGS1PTGS2 | |
| SCHEMBL9448868 | 0.83 | ALOX5 (0.46) | ALOX5S1PR1S1PR3ALOX12PTGS1 | |
| SCHEMBL9448809 | 0.79 | ALOX5 (0.46) | ALOX5ALOX12PTGS1PTGS2 | |
| SCHEMBL9729685 | 0.75 | ALOX5 (1.00) | ALOX5ALOX12PTGS1PTGS2 | |
| SCHEMBL9218186 | 0.75 | ALOX5 (0.47) | ALOX5PTGS2 | |
| SCHEMBL9621234 | 0.74 | TP53 (0.44) | S1PR1S1PR3 | |
| SCHEMBL9167051 | 0.73 | ALOX5 (0.58) | ALOX5S1PR1S1PR3PTGS1PTGS2 | |
| SCHEMBL2622583 | 0.73 | CYP11B1 (0.49) | S1PR1S1PR3PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254731-A | Enzyme inhibitors; leukotriene disorders | GRUENENTHAL GMBH (DE) | 1993-10-19 | — | — | US | disclosed |