Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 15/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9448945 | 0.82 | ALOX5 (0.61) | ALOX5PTGS1PTGS2ALOX12 | |
| SCHEMBL9448870 | 0.81 | ALOX5 (0.48) | ALOX5PTGS1PTGS2ALOX12 | |
| SCHEMBL9448907 | 0.79 | ALOX5 (0.60) | ALOX5PTGS1PTGS2ALOX12 | |
| SCHEMBL9448868 | 0.78 | ALOX5 (0.46) | ALOX5PTGS1PTGS2ALOX12 | |
| SCHEMBL17815599 | 0.73 | MCHR1 (0.41) | — | |
| SCHEMBL9218186 | 0.72 | ALOX5 (0.47) | ALOX5PTGS2 | |
| SCHEMBL18710317 | 0.71 | CCR4 (0.34) | — | |
| SCHEMBL9215916 | 0.70 | HRH3 (0.38) | PTGS1PTGS2PARP10 | |
| SCHEMBL9214803 | 0.68 | ALOX5 (0.48) | ALOX5 | |
| SCHEMBL8544280 | 0.68 | FURIN (0.52) | ALOX5PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254731-A | Enzyme inhibitors; leukotriene disorders | GRUENENTHAL GMBH (DE) | 1993-10-19 | — | — | US | disclosed |