Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9152444 | 0.90 | TSHR (0.40) | MMP1MMP2TSHRACHETP53 | |
| SCHEMBL7921422 | 0.79 | ACHE (0.35) | MMP1MMP2CYP1A2ACHETDP1 | |
| SCHEMBL7915207 | 0.78 | PPARD (0.44) | MMP1MMP2TSHRCYP1A2TP53 | |
| SCHEMBL18311508 | 0.74 | MMP1 (0.39) | MMP1MMP2TSHRCYP1A2ACHE | |
| SCHEMBL17039331 | 0.74 | MMP1 (0.42) | MMP1MMP2TSHRCYP1A2ACHE | |
| SCHEMBL10356358 | 0.73 | CA12 (0.38) | MMP1MMP2CYP1A2ACHECA12 | |
| SCHEMBL8751304 | 0.73 | MMP1 (0.35) | MMP1MMP2TSHRCYP1A2L3MBTL1 | |
| SCHEMBL575926 | 0.72 | MMP1 (0.42) | MMP1MMP2TSHRACHETP53 | |
| SCHEMBL17034252 | 0.72 | TP53 (0.38) | MMP1MMP2TSHRCYP1A2TP53 | |
| SCHEMBL8368499 | 0.72 | MMP1 (0.34) | MMP1MMP2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5190934-A | Treatment of cognitive and memory disorders | CIBA-GEIGY CORPORATION (US) | 1993-03-02 | — | — | US | disclosed |