SCHEMBL9449249

SCHEMBL9449249

CC(C)(CC(=O)O)c1ccc(OC(F)F)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.51
ALOX15 P16050 1/20 0.46
GFER P55789 1/20 0.46
ADAM17 P78536 1/20 0.46
TP53 P04637 1/20 0.43
GAA P10253 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.42
HTT P42858 1/20 0.42
PPARG P37231 2/20 0.41
PPARA Q07869 2/20 0.41
LMNA P02545 2/20 0.41
POLB P06746 1/20 0.41
DAGLA Q9Y4D2 1/20 0.40
ALDH1A1 P00352 2/20 0.40
MRGPRX4 Q96LA9 1/20 0.40
CYP2C19 P33261 1/20 0.40
HIF1A Q16665 1/20 0.40
CACNA1H O95180 1/20 0.39
EPHX2 P34913 1/20 0.39
HDAC3 O15379 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10837776 0.80 ALOX15 (0.43) ATMALOX15GFERADAM17TP53
SCHEMBL2721820 0.80 ALDH1A1 (0.51) ALOX15SMN1; SMN2HTTLMNAALDH1A1
SCHEMBL10836381 0.78 ALOX15 (0.50) ATMALOX15GFERADAM17TP53
SCHEMBL18746248 0.78 NPC1 (0.53) ALOX15GFERADAM17TP53GAA
SCHEMBL9632901 0.76 ATM (0.47) ATMALOX15GFERADAM17TP53
SCHEMBL9632889 0.76 ATM (0.47) ATMALOX15GFERADAM17TP53
SCHEMBL7566897 0.75 CYP2C19 (0.47) SMN1; SMN2HTTCYP2C19HIF1AL3MBTL1
SCHEMBL22458451 0.75 CYP2C19 (0.47) HTTLMNAALDH1A1CYP2C19HIF1A
SCHEMBL10914051 0.75 CYP2C19 (0.50) SMN1; SMN2ALDH1A1CYP2C19HIF1A
SCHEMBL18699913 0.75 CNR2 (0.40) ATMALOX15GFERADAM17TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5202503-A Chemical intermediates for the preparation of pesticides BASF AKTIENGESELLSCHAFT (DE) 1993-04-13 US disclosed