Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9632901 | 1.00 | ATM (0.47) | ATMALOX15GFERADAM17HTT | |
| SCHEMBL10541395 | 0.81 | ATM (0.47) | ATMALOX15GFERADAM17HTT | |
| SCHEMBL11117316 | 0.80 | ALDH1A1 (0.50) | ALOX15L3MBTL1PPARALMNAALDH1A1 | |
| SCHEMBL10836381 | 0.80 | ALOX15 (0.50) | ATMALOX15GFERADAM17HTT | |
| SCHEMBL1821731 | 0.77 | CXCR2 (0.44) | PPARAPOLBALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL24534819 | 0.77 | ATM (0.56) | ATMALOX15GFERADAM17HTT | |
| SCHEMBL18746248 | 0.76 | NPC1 (0.53) | ALOX15GFERADAM17HTTTP53 | |
| SCHEMBL5794046 | 0.76 | KDM4E (0.44) | HTTHDAC3HDAC1HDAC2L3MBTL1 | |
| SCHEMBL9449249 | 0.76 | ATM (0.51) | ATMALOX15GFERADAM17HTT | |
| SCHEMBL10969483 | 0.76 | ALOX15 (0.46) | ATMALOX15GFERADAM17HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5093358-A | MACROCYCLIC PLANT ACARICIDES | CIBA-GEIGY CORP. (US) | 1992-03-03 | — | — | US | disclosed |