Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | CES2 | O00748 | 3/20 | 0.33 |
| ▸ | CES1 | P23141 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | ATM | Q13315 | 2/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30080293 | 0.82 | ALDH1A1 (0.52) | HPGDACHENR1H2NR1H3ALDH1A1 | |
| SCHEMBL20010800 | 0.82 | CES2 (0.52) | HPGDACHENR1H2NR1H3CES2 | |
| SCHEMBL105892 | 0.80 | HPGD (0.74) | HPGDALDH1A1CES2CES1TP53 | |
| SCHEMBL11910715 | 0.80 | HPGD (0.50) | HPGDACHEALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6853105 | 0.78 | HPGD (0.46) | HPGDACHENR1H2NR1H3ALDH1A1 | |
| SCHEMBL5470502 | 0.78 | PARP10 (0.50) | HPGDALDH1A1TSHRSMN1; SMN2MAPT | |
| SCHEMBL9716978 | 0.78 | HPGD (0.46) | HPGDACHENR1H2NR1H3ALDH1A1 | |
| SCHEMBL9279020 | 0.76 | LMNA (0.50) | HPGDACHENR1H2NR1H3ALDH1A1 | |
| SCHEMBL9563126 | 0.75 | ALDH1A1 (0.70) | HPGDALDH1A1LMNACES2CES1 | |
| SCHEMBL9959826 | 0.75 | HSD17B1 (0.59) | HPGDLMNASMN1; SMN2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6020426-A | BLOCK OR GRAFT COPOLYMER | FUJI XEROX CO., LTD. (JP) | 2000-02-01 | — | — | US | disclosed |