Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | CTSL | P07711 | 4/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 3/20 | 0.51 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14377773 | 0.82 | SMN1; SMN2 (0.60) | SMN1; SMN2GAARAB9ACTSLCTSS | |
| SCHEMBL3927028 | 0.79 | CTSL (0.71) | GAARAB9ACTSLCTSSCTSK | |
| SCHEMBL28790851 | 0.79 | CTSL (0.71) | GAARAB9ACTSLCTSSCTSK | |
| SCHEMBL25004063 | 0.78 | CTSL (0.62) | RAB9ACTSLCTSSCTSKACE | |
| SCHEMBL6942271 | 0.78 | GAA (0.60) | SMN1; SMN2GAARAB9ACTSLCTSS | |
| SCHEMBL1793176 | 0.76 | GAA (0.76) | GAARAB9ACTSLCTSSCTSK | |
| SCHEMBL2461492 | 0.76 | GAA (0.76) | GAARAB9ACTSLCTSSCTSK | |
| SCHEMBL31206887 | 0.76 | GAA (0.76) | GAARAB9ACTSLCTSSCTSK | |
| SCHEMBL8056323 | 0.76 | CTSL (0.58) | CTSLCTSSCTSKACEPSMB5 | |
| SCHEMBL16523134 | 0.75 | CTSL (0.65) | GAARAB9ACTSLCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0544812-A1 | BISPHOSPHONIC ACID DERIVATIVES AS ANTI-ARTHRITIC AGENTS. | UPJOHN CO (US) | 1993-06-09 | — | — | EP | claimed |