Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8786659 | 1.00 | KDR (0.31) | KDR | |
| Ilonidap SCHEMBL42518 | 0.84 | ALDH1A1 (0.35) | — | |
| Ilonidap SCHEMBL8587853 | 0.84 | ALDH1A1 (0.35) | — | |
| Ilonidap SCHEMBL8587849 | 0.84 | ALDH1A1 (0.35) | — | |
| Ilonidap SCHEMBL8788348 | 0.83 | ALDH1A1 (0.34) | — | |
| Ilonidap SCHEMBL8788134 | 0.83 | ALDH1A1 (0.34) | — | |
| Ilonidap SCHEMBL9284472 | 0.83 | ALDH1A1 (0.34) | — | |
| Ilonidap SCHEMBL8788132 | 0.83 | ALDH1A1 (0.34) | — | |
| SCHEMBL8788515 | 0.82 | — | — | |
| SCHEMBL8788511 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5270331-A | Prodrugs of antiinflammatory 3-acyl-2-oxindole-1-carboxamides | PFIZER, INC. (US) | 1993-12-14 | — | — | US | disclosed |