⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8788515 | 1.00 | — | — | |
| SCHEMBL8788471 | 0.88 | ALDH1A1 (0.34) | — | |
| SCHEMBL8788475 | 0.88 | ALDH1A1 (0.34) | — | |
| SCHEMBL8786659 | 0.82 | KDR (0.31) | — | |
| SCHEMBL9449352 | 0.82 | KDR (0.31) | — | |
| SCHEMBL8786989 | 0.78 | LMNA (0.32) | — | |
| SCHEMBL8787758 | 0.77 | MEN1 (0.36) | — | |
| SCHEMBL8787752 | 0.77 | MEN1 (0.36) | — | |
| SCHEMBL8787452 | 0.74 | SCN5A (0.33) | — | |
| SCHEMBL8787449 | 0.74 | SCN5A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0681580-B1 | PRODRUGS OF ANTIINFLAMMATORY 3-ACYL-2-OXINDOLE-1-CARBOXAMIDES | PFIZER (US) | 1997-07-09 | — | — | EP | disclosed |
| US-5270331-A | Prodrugs of antiinflammatory 3-acyl-2-oxindole-1-carboxamides | PFIZER, INC. (US) | 1993-12-14 | — | — | US | disclosed |