Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | HRH1 | P35367 | 2/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | EDNRB | P24530 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9449363 | 0.87 | EGFR (0.45) | MYCHTR7HTR2BHTR2AEGFR | |
| SCHEMBL8993450 | 0.83 | HTR2A (0.45) | HTR2AEGFRHRH1CA1CA2 | |
| SCHEMBL9449370 | 0.83 | TDO2 (0.37) | MYCHTR7HTR2BHTR2AEGFR | |
| Hydrochloric Acid SCHEMBL5358965 | 0.80 | HTR2A (0.42) | MYCHTR7HTR2BHTR2AHRH1 | |
| Hydrochloric Acid SCHEMBL5363315 | 0.80 | HTR2A (0.42) | MYCHTR7HTR2BHTR2AHRH1 | |
| SCHEMBL9449558 | 0.79 | EGFR (0.40) | MYCHTR7HTR2BEGFRCYP1A2 | |
| SCHEMBL9449421 | 0.77 | HTR2A (0.42) | MYCHTR7HTR2BHTR2APBRM1 | |
| SCHEMBL9449877 | 0.75 | HTR2A (0.36) | MYCHTR7HTR2BHTR2AHRH1 | |
| SCHEMBL27335604 | 0.75 | HTR2A (0.44) | MYCHTR7HTR2BHTR2APBRM1 | |
| SCHEMBL8857191 | 0.75 | HTR2A (0.42) | MYCHTR7HTR2BHTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0531443-A4 | METHODS FOR TREATING INFLAMMATION AND COMPOUNDS AND COMPOSITIONS SUITABLE FOR USE THEREIN | — | 1993-04-21 | — | — | EP | disclosed |
| EP-0531443-A1 | METHODS FOR TREATING INFLAMMATION AND COMPOUNDS AND COMPOSITIONS SUITABLE FOR USE THEREIN | NOVA PHARMACEUTICAL CORPORATION (US) | 1993-03-17 | — | — | EP | disclosed |
| US-5079260-A | Side effect reduction; fluorene derivatives | NOVA PHARMACEUTICAL CORPORATION (US) | 1992-01-07 | — | — | US | disclosed |
| WO-1991018596-A1 | METHODS FOR TREATING INFLAMMATION AND COMPOUNDS AND COMPOSITIONS SUITABLE FOR USE THEREIN | WEITZBERG MOSHE (US) | 1991-12-12 | — | — | WO | disclosed |