Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9346770 | 0.99 | AGTR1 (0.41) | AGTR1KDM4EAGTR2 | |
| Hydrochloric Acid SCHEMBL9350392 | 0.88 | PPARG (0.39) | AGTR1 | |
| SCHEMBL684181 | 0.84 | AGTR1 (0.50) | AGTR1KDM4EAGTR2 | |
| SCHEMBL9427044 | 0.83 | PTGES (0.33) | AGTR1KDM4E | |
| SCHEMBL7284844 | 0.83 | AGTR1 (0.43) | AGTR1AGTR2 | |
| SCHEMBL9308629 | 0.82 | HDAC1 (0.47) | AGTR1AGTR2 | |
| Hydrochloric Acid SCHEMBL9350439 | 0.82 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL9308540 | 0.81 | MEN1 (0.45) | AGTR1AGTR2 | |
| SCHEMBL9662889 | 0.81 | AGTR1 (0.39) | AGTR1AGTR2 | |
| Hydrochloric Acid SCHEMBL9664123 | 0.80 | AGTR1 (0.38) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5217976-A | Hypotensive agents, congestive heart failure | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-06-08 | — | — | US | claimed |