Phenamino Methyl Acetic Acid

Phenamino Methyl Acetic Acid

SCHEMBL9449485

O=C(O)CCNc1ccccc1.O=S(=O)(O)CCNc1ccccc1

nearest known ligand 0.50

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.50
POLB P06746 2/20 0.50
MEN1 O00255 2/20 0.50
NSD2 O96028 1/20 0.50
BLM P54132 1/20 0.50
RXFP1 Q9HBX9 1/20 0.50
CDC25A P30304 1/20 0.48
CDC25B P30305 1/20 0.48
ALDH1A1 P00352 6/20 0.46
HSD17B10 Q99714 3/20 0.46
HPGD P15428 2/20 0.46
CA12 O43570 2/20 0.46
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
CA9 Q16790 2/20 0.46
FFAR1 O14842 2/20 0.45
TBXA2R P21731 1/20 0.43
SIRT5 Q9NXA8 2/20 0.43
MAPT P10636 3/20 0.42
KDM4E B2RXH2 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1608002 0.89 ALDH1A1 (0.52) BLMALDH1A1CA12CA1CA2
Phenamino Methyl Acetic Acid SCHEMBL433918 0.86 POLB (0.59) KMT2APOLBMEN1NSD2BLM
SCHEMBL10491012 0.79 POLB (0.57) KMT2APOLBMEN1NSD2BLM
Phenamino Methyl Acetic Acid SCHEMBL28795445 0.79 ALDH1A1 (0.56) KMT2APOLBMEN1NSD2BLM
SCHEMBL1607864 0.79 ALDH1A1 (0.59) ALDH1A1CA12CA1CA2CA9
SCHEMBL246721 0.79 ALDH1A1 (0.59) ALDH1A1CA12CA1CA2CA9
SCHEMBL18775962 0.78 TOP2A (0.47) POLBALDH1A1CA12CA1CA2
SCHEMBL1607516 0.77 ALDH1A1 (0.57) ALDH1A1CA12CA2CA9MAPT
SCHEMBL8969604 0.77 ALDH1A1 (0.57) ALDH1A1CA12CA1CA2CA9
SCHEMBL8969772 0.77 ALDH1A1 (0.57) ALDH1A1CA12CA2CA9MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5227475-A WATER-SOLUBLE FIBER-REACTIVE DYESTUFFS CONTAINING A CYANAMIDO-SUBSTITUTED TRIAZINYLAMINO-GROUPING, AND A PROCESS FOR DYEING WITH THE USE OF THESE DYES HOECHST AKTIENGESELLSCHAFT (DE) 1993-07-13 US disclosed