SCHEMBL1608002

SCHEMBL1608002

O=S(=O)(O)CCNc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.52
MAPT P10636 2/20 0.52
CA2 P00918 5/20 0.47
CA12 O43570 4/20 0.47
CA9 Q16790 4/20 0.47
L3MBTL1 Q9Y468 1/20 0.45
CA1 P00915 4/20 0.41
ACP1 P24666 2/20 0.41
DRD4 P21917 1/20 0.41
CYP2D6 P10635 1/20 0.41
KDM4E B2RXH2 2/20 0.40
LMNA P02545 2/20 0.40
CYP3A4 P08684 1/20 0.40
GAA P10253 1/20 0.40
BLM P54132 1/20 0.40
GFER P55789 1/20 0.40
PMP22 Q01453 1/20 0.40
HDAC3 O15379 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC2 Q92769 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenamino Methyl Acetic Acid SCHEMBL9449485 0.89 KMT2A (0.50) ALDH1A1MAPTCA2CA12CA9
SCHEMBL1607864 0.88 ALDH1A1 (0.59) ALDH1A1MAPTCA2CA12CA9
SCHEMBL246721 0.88 ALDH1A1 (0.59) ALDH1A1MAPTCA2CA12CA9
SCHEMBL1607454 0.86 ALDH1A1 (0.57) ALDH1A1MAPTCA2CA12CA9
SCHEMBL1606652 0.86 ALDH1A1 (0.57) ALDH1A1MAPTCA2CA12CA9
SCHEMBL8969604 0.86 ALDH1A1 (0.57) ALDH1A1MAPTCA2CA12CA9
SCHEMBL1333377 0.86 ALDH1A1 (0.57) ALDH1A1MAPTCA2CA12CA9
SCHEMBL1607516 0.86 ALDH1A1 (0.57) ALDH1A1MAPTCA2CA12CA9
SCHEMBL8969772 0.86 ALDH1A1 (0.57) ALDH1A1MAPTCA2CA12CA9
SCHEMBL8968708 0.85 ALDH1A1 (0.55) ALDH1A1MAPTCA2CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 238 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103261336-B Surface modified organic black pigments, surface modified carbon blacks, pigment mixtures using them, and low dielectric black dispersions, coatings, films, black matrices, and devices containing same CABOT CORP 2015-04-01 CN claimed
WO-2012168458-A1 ZWITTERIONIC COMPOUNDS USEFUL AS CATALYSTS FOR ESTERIFICATION REACTIONS AND PROCESSES FOR THEIR PRODUCTION ECOSYNTH BVBA (BE) 2012-12-13 WO claimed
US-8313892-B2 Multi-layer body, method for forming resist pattern, method for manufacturing device having pattern by fine processing and electronic device FUJITSU LIMITED (JP) 2012-11-20 US claimed
US-7799092-B2 Composition for simultaneously bleaching and dyeing keratin fibers, comprising at least one anionic or nonionic direct dye and at least one associative polymer L'OREAL S.A. (FR) 2010-09-21 US claimed
US-7736395-B2 direct dyes L'OREAL S.A. (FR) 2010-06-15 US claimed
US-20070033744-A1 Anhydrous composition; nonionic or anionic direct dye, associative polymer, peroxygenated salt, and alkaline agent; hair dyes suitable for dark hair; easy to use and can produce chromatic and fast coloration L'OREAL S.A. (FR) 2007-02-15 US claimed
US-20070033743-A1 direct dyes L'OREAL S.A. (FR) 2007-02-15 US claimed
WO-2006060654-A2 PESTICIDAL COMPOSITIONS AND METHODS DIVERGENCE, INC. (US) 2006-06-08 WO claimed
US-20050203067-A1 Pesticidal compositions and methods DIVERGENCE, INC. 2005-09-15 US claimed
EP-0776947-B1 Fiber-reactive dyestuffs, their preparation and use CIBA SC HOLDING AG (CH) 2000-04-26 EP claimed
US-5837827-A Fibre-reactive dyes, their preparation and their use CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-11-17 US claimed
EP-0776947-A1 Fiber-reactive dyestuffs, their preparation and use Ciba SC Holding AG (CH) 1997-06-04 EP claimed
US-4065255-A HUMAN HAIR L'OREAL (FR) 1977-12-27 US claimed
CN-112831541-B Creatinine kit with good stability and capable of rapidly eliminating drug interference 中山标佳生物科技有限公司 2024-10-11 CN disclosed
CN-112501244-B Preparation method of creatinine kit capable of eliminating interference of calcium dobesilate and phenol sulfoethylamine drugs 中山标佳生物科技有限公司 2024-10-11 CN disclosed
CN-112626170-B Uric acid kit for rapidly and simply eliminating drug interference and preparation method thereof 中山标佳生物科技有限公司 2024-08-27 CN disclosed
US-4325705-A Anthraquinone reactive dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1982-04-20 US disclosed
US-4256882-A XANTHYLIUM DYES, POLYAMIDES, CELLULOSE BAYER AKTIENGESELLSCHAFT (DE) 1981-03-17 US disclosed
EP-0012342-A1 Anthraquinone reactive dyestuffs and their use in dyeing and printing materials that contain hydroxyl groups or amide groups BAYER AG (DE) 1980-06-25 EP disclosed
EP-0012341-A1 Anthraquinone reactive dyestuffs and their use in dyeing materials that contain hydroxyl or amide groups BAYER AG (DE) 1980-06-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070033744-A1 Anhydrous composition; nonionic or anionic direct dye, associative polymer, peroxygenated salt, and alkaline agent; hair dyes suitable for dark hair; easy to use and can produce chromatic and fast coloration KRT18, BRD7, KAT7 ALDH1A1 930/4885MAPT 730/4885CA2 413/4885
US-20070033743-A1 direct dyes KRT18, DSG1, DSP ALDH1A1 385/4885MAPT 1332/4885CA2 448/4885
US-20050203067-A1 Pesticidal compositions and methods ACHE, DDT, PTMS ALDH1A1 3205/4885MAPT 3378/4885CA2 701/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.